https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29666 10 mg/L, or who were taking anti-inflammatory medications or n-3PUFA supplements, 126 participants (age 77.6 ± 7.3 years; females, 46%) were included in the analysis. After multivariate adjustments, O3I was inversely associated with CRP (β = −0.209, p < 0.05) and monocyte cell counts (β = −0.205, p < 0.05), and total n-3PUFA was inversely related to WBC (β = −0.238, p < 0.05), neutrophils (β = −0.212, p < 0.05) and monocytes (β = −0.246, p < 0.05). However no association between fibrinogen and O3I or total n-3PUFA was detected. Conclusions: This study demonstrated a negative association between O3I and biomarkers of inflammation in an older population. The findings support a potential role for n-3PUFA supplementation in the management of inflammatory diseases.]]> Wed 11 Apr 2018 16:52:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29661 Wed 11 Apr 2018 16:03:15 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29551 p=0.06), WC (r = −0.118, p < 0.01) and waist-to-hip ratio (WHR; r = −0.149, p < 0.001). Stratification of data by sex (females, n = 349; males, n = 271) indicated that these associations were sex-specific. Females displayed an inverse association between the omega-3 index and BMI (r = −0.146, p < 0.01) and WC (r = −0.125, p < 0.05). In contrast, no significant association between the omega-3 index and anthropometric measures was detected in males. After correcting for the potentially confounding effects of age, household income, fish oil supplement status, daily dietary energy intake and total physical activity times, the omega-3 index was inversely associated with BMI and WC in females but not males. Conclusions: Omega-3 status was associated with weight status, particularly in older women but not in men. These results suggest the need for sex-based intervention trials to examine the role of dietary intake and/or supplementation of LCn-3PUFA in weight management of older adults.]]> Wed 09 Mar 2022 16:02:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12427 2.25) children (33%) had an omega-3 index of < 4.0 (high risk) compared with non-obese children (BMI z-score < 2.25) (17%). Simultaneously, the number of children with a higher omega-3 index (6.0–8.0 lower risk) was lower in the obese (13%) versus non-obese children (25%, respectively). A moderate, but statistically significant correlation was found between O3I and fasting insulin level (r = −0.3, P = 0.03) and with homeostatic model assessment (HOMA) scores (r = −0.3, P = 0.04). Conclusion: The observed association between the omega-3 index, weight status and insulin resistance in children highlights the importance of omega-3 fatty acids in the prevention of obesity-related chronic diseases in later life. The results presented merits confirmation in a larger sample of obese children.]]> Sat 24 Mar 2018 08:17:46 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26621 Sat 24 Mar 2018 07:34:00 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38154 Mon 29 Jan 2024 17:46:57 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38015 Fri 23 Jul 2021 15:33:53 AEST ]]>